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The antiviral Interferon pathway drives astrocyte aging and motor decline

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Year: 2025
Type: preprint
Source: bioRxiv (Cold Spring Harbor Laboratory)
DOI: 10.1101/2025.11.12.688147
Authors: Lara Labarta-Bajo, Ayesha R Thanawalla, Irene L Gutierrez, Su May Lei Soe, Brent Y Chick, Ioanna Andritsogianni, Setareh Metanat, Diana C Hargreaves, Susan M Kaech, Eiman Azim, Nicola J Allen
Institution: Salk Institute for Biological Studies
Language: English

Topic: Neuroinflammation and Neurodegeneration Mechanisms
Subfield: Neurology
Field: Neuroscience
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: Kavli Foundation, National Institutes of Health, National Institute of Neurological Disorders and Stroke
Awards: Spinal Circuits for the Control of Dextrous Movement, Targeting astrocytes to prevent motor decline in aging
OpenAlex ID: W4416247669
Cites: 80
Cited by: 1
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