Year: 2025
Type: article
Abstract: Atopic dermatitis is a chronic inflammatory disease that affects skin but is frequently associated with a variety of ophthalmological manifestations that can have a significant impact on patients quality of life. This review aims to gather current evidence on the pathophysiology, epidemiology, and clinical spectrum of ocular complications in AD, including eyelid dermatitis, blepharitis, conjunctivitis, keratoconus, cataract, retinal detachment, and dupilumab-associated ocular surface disease (DAOSD). Almost half of AD patients will experience ocular complications with main risk factors being disease duration and involvement of the periocular area. Diagnosis should primarily be based on thorough clinical evaluations and ophthalmological assessment. Management requires use of both topical and systemic drugs, patient education and in the most severe cases surgical intervention. Multidisciplinary cooperation most importantly between dermatologists and ophthalmologists is key for early diagnosis, effective treatment and prevention of complications associated with vision loss. Regular ocular screening is recommended for all patients with AD, especially those who are being treated with dupilumab.
Source: Quality in Sport
Authors: Szymon Kosek, Justyna Klonowska, Radosław Jan Walkowski, Weronika Wasiniewska, Marcin Barański, Tomasz Kandefer, Maria Izabela Sroka
Institution: Medical University of Warsaw
Language: English
Subfield: Dermatology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4416249166
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