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Prognostic Implications of Pneumothorax and Pneumomediastinum in COVID-19 Pneumonia: A Cross-Sectional Analysis

Year: 2025
Type: article
Study design: Observational Study
Abstract: Introduction: The prognostic implications of developing pneumothorax (PT) or pneumomediastinum (PM) in COVID-19 pneumonia remain a topic of debate, with current literature showing conflicting data. We aimed to assess mortality rates and the characteristics of patients with COVID-19 pneumonia who developed these complications compared to those who did not. Methods: We analyzed data and outcomes for patients aged 18 years or older who were admitted for COVID-19 pneumonia to a tertiary care referral center in Lebanon. Results: . 24.5%). Most events occurred in patients with severe lung involvement on computed tomography (CT). Only three patients died within the first 48 hours after the development of an event. Incidence was higher in patients who were overweight or obese and increased with age. Distribution was similar between both genders. Ventilation data showed that 79% of events occurred during non-invasive or invasive mechanical ventilation. Discussion: Barotrauma events, including PT and PM in COVID-19 pneumonia, were associated with significantly higher mortality and appear to reflect more severe lung involvement. Mortality was not directly caused by the events themselves. A significant proportion occurred in patients on supplemental oxygen or high-flow nasal cannula (21%), highlighting the need for a high index of suspicion for such events even in non-ventilated patients. Conclusion: There is a strong association between the development of PT and/or PM and mortality in COVID-19 pneumonia.
DOI: 10.2174/0118743064418513251104054134
Authors: Dany Gaspard, Nadine Yared, Reem Wehbe, Elias Horanieh, Tarek Bou Dargham, Mohamad Bahij Moumneh, Christine Atallah, Mohammad Fawaz
Language: English
Field: Medicine
Open Access status: diamond
OpenAlex ID: W4416252536
FWCI:
Cites: 19
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