Work

Co‐Occurrence of Endogenous and Exogenous Cushing's Syndromes: Does “Double Cushing Syndrome” Really Exist? A Case Report

Year: 2025

Type: article

Abstract: Double Cushing syndrome exists: exogenous steroid use can mask concurrent adrenal hypercortisolism. When symptoms persist and cortisol remains high after tapering or stopping prescribed glucocorticoids, an endogenous source is likely. Early recognition with ACTH testing, dexamethasone suppression, and adrenal imaging reduces misdiagnosis, favors timely surgery, and supports safe tapering.

Source: Clinical Case Reports

DOI: 10.1002/ccr3.71419

Authors: Reza Amani‐Beni, Atiyeh Karimi Shervedani, Bahar Darouei, Matin Noroozi, Maryam Heidarpour

Institution: Isfahan University of Medical Sciences

Language: English

Topic: Pituitary Gland Disorders and Treatments

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,820