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Severe Bleeding From Portal Hypertension in a Young Patient With Common Variable Immunodeficiency-Associated Nodular Regenerative Hyperplasia

Year: 2025

Type: article

Abstract: Common variable immunodeficiency (CVID) is a primary immunodeficiency disorder causing hypogammaglobulinemia. Although rare, nodular regenerative hyperplasia is the most common liver complication in CVID, which can progress to noncirrhotic portal hypertension. We report a case of a young male with CVID presenting with recurrent parastomal bleeding secondary to noncirrhotic portal hypertension from CVID-associated nodular regenerative hyperplasia.

Source: ACG Case Reports Journal

DOI: 10.14309/crj.0000000000001891

Authors: Vijayvardhan Kamalumpundi, Darine Daher, Zongming Eric Chen, Sarah Khan, Navreet Chowla

Institution: Mayo Clinic

Language: English

Topic: Liver Disease and Transplantation

Subfield: Hepatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4416278150

FWCI:

Cites: 14

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