The Efficacy of Topical Hyaluronic Acid 0.2% in the Management of Symptomatic Oral Lichen Planus
Year: 2025
Type: article
Study design: Clinical Trial
Abstract: This study aimed to evaluate the efficacy of 0.2% topical hyaluronic acid in the management of symptomatic oral lichen planus (OLP). This prospective interventional study was conducted at the Department of Dermatology, Services Institute of Medical Sciences / Services Hospital, Lahore, Pakistan. Fourteen patients with symptomatic OLP lesions applied hyaluronic acid in orabase gel for 28 days. Patients were followed up weekly, and the final assessment was performed at the end of four weeks. The baseline mean modified oral mucositis index (MOMI) score decreased from 2.06 ± 0.41 to 0.27 ± 0.34 for cheek lesions and from 1.50 ± 00 to 0.25 ± 0.25 for lip lesions. The mean change in MOMI score for cheek was 1.79 ± 0.40 and for lips was 1.25 ± 0.25. These findings suggest that topical hyaluronic acid 0.2% is effective in the treatment of symptomatic OLP and can be easily and safely used as an adjuvant treatment alongside other topical and systemic treatments. Key Words: Oral lichen planus, Topical hyaluronic acid, Modified oral mucositis index, Oral ulcers.
Authors: Saadiya Siddiqui, Ayesha Chatta, Faria Altaf
Institutions: Services Institute of Medical Sciences, Services Hospital
Language: English
Subfield: Periodontics
Field: Dentistry
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4416282589
FWCI:
Cites:
Cited by:
Related to: