Work

Paper-Based Device for the Colorimetric Determination of Glucose in Whole-Blood Samples Using a Smartphone

Year: 2025

Type: article

Abstract: In many clinical settings, there is a great need for rapid, simple, and reliable diagnostic tools for the detection and quantification of various biomarkers. These tools enable early medical decisions, which can significantly influence patient recovery. Paper-based analytical devices (PADs) have become promising platforms for rapid and low-cost diagnostic testing in recent years. Among the most important biomarkers is glucose, a key metabolite involved in numerous physiological processes, which allows for the diagnosis and control of diabetes, the prevention of serious long-term complications such as cardiovascular disease, and the monitoring of the effect of medication, diet, and exercise on sugar levels in these patients. A fundamental step in detecting this marker in laboratories is the separation of plasma from whole blood. Several studies have demonstrated the successful integration of plasma separation in μPADs. This work presents the development of a paper-based device for the colorimetric detection of glucose in whole-blood samples, allowing plasma separation and using a smartphone to perform quantitative determination.

Source: Bioengineering

DOI: 10.3390/bioengineering12111250

Authors: Lara Bianca Agostina Boga, Katia Gianni, Mariano Nicolás Aleman, Marcos Sebastián Almirón Arroyo, Rossana Elena Madrid

Institutions: National University of Tucumán, Consejo Nacional de Investigaciones Científicas y Técnicas, Instituto Superior de Investigaciones Biológicas

Language: English

Topic: Biosensors and Analytical Detection

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,258