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Burden of Severe Disease Associated With Influenza, SARS‐CoV‐2 and RSV in Spain During the 2024–2025 Winter Season

Year: 2025
Type: article
Study design: Observational Study
Abstract: We estimated the burden of influenza, SARS-CoV-2 and RSV from patients hospitalized with acute respiratory infection systematically tested between weeks 40/2024 and 20/2025 in Spain. The hospitalization rate per 100,000 was highest for influenza [67.5 (95% Confidence Interval: 52.5-87.3)] followed by RSV [46.6 (35.4-62.2)] and SARS-CoV-2 [15.8 (10.2-24.6)]. Hospitalization rates peaked in ≥ 60-year-olds and < 5-year-olds, ICU admissions in < 1-year-olds and deaths in ≥ 80-year-olds. Hospitalization for SARS-CoV-2 at 80-85 years was comparable to influenza at 60-65 years, potentially signaling the appropriateness of increasing the COVID-19 vaccination age cut-off. RSV prevention appeared a priority in < 5-year-olds but substantial preventive potential was identified in the elderly.
Authors: Daniel Aguilar Figueroa, Gloria Pérez‐Gimeno, Olivier Núñez, Susana Monge, The SiVIRA Surveillance and Vaccine Effectiveness Working Group
Language: English
Subfield: Epidemiology
Field: Medicine
Open Access status: gold
Estimated APC paid: $4,840
OpenAlex ID: W4416307490
FWCI: 2.492
Cites: 12
Cited by: 4
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