Estimation of Serum Calcium and Vitamin D Levels in Patients with Benign Paroxysmal Positional Vertigo
Year: 2025
Type: article
Study design: Observational Study
Abstract: Background: Benign paroxysmal positional vertigo (BPPV) is the most common cause of peripheral vertigo. Calcium homeostasis and vitamin D metabolism may play roles in its pathophysiology. BPPV is associated with the homeostasis of calcium. Aim and objectives: The purpose of this study was to estimate the blood levels of vitamin D and calcium in BPPV patients and investigate the relationship between them. Patients and methods: This cross-sectional controlled study included 80 subjects attending at otorhinolaryngology department, Al-Azhar University Hospital in Damietta.The patients will be divided into 2 groups, group 1 that will include 40 patients diagnosed with BPPV, and group 2 that will include 40 healthy individuals Results: No statistically significant differences were found between the BPPV and control groups in serum calcium or vitamin D levels. However, a significant negative correlation was observed between the frequency of BPPV episodes and vitamin D levels (r = -0.375). The most common BPPV type was posterior semicircular canal (70%). Conclusion: The current study's findings demonstrated that the study population's blood vitamin D levels were typically low. There was no association found between BPPV and blood calcium and vitamin D levels. This might be as a result of the general population in this region having generally lower blood levels of vitamin D. However, a statistically significant negative association was found between blood vitamin D levels and the number of BPPV episodes, indicating that the likelihood of BPPV recurrence increases as vitamin D levels fall.
Authors: Yossuf Mohamed Reda, Elshahat Ibrahim Ismail Elshokry, Mahmoud Farag Mohamed Salem, mohamed hussein abdelazim
Institutions: Al-Azhar University, Mansoura University
Language: English
Subfield: Neurology
Field: Neuroscience
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $150
OpenAlex ID: W4416334064
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