Year: 2025
Type: article
Abstract: This commentary summarizes recently published research, giving several important findings.Deficiency of skeletal muscle appears, like excess of visceral fat, to strongly contribute to the development of diabetes.Concerns about GLP-1RA in contributing to low muscle mass may be overstated, with the benefits of the class appearing to outweigh adverse effects; however, approaches to prevention of muscle loss with GLP-1RA and with diabetes itself are important.Low muscle strength is a strong predictor of mortality and frailty; and resistance exercise may be a key approach in patient management.Cardiovascular risks differ between type 1 diabetes (T1D) and type 2 diabetes (T2D), with risk reduction important for both.Obesity treatments (semaglutide, tirzepatide, and bariatric surgery) generally lower the risk of obesity-related cancers, but bariatric surgery may increase the risk for procedure-related cancers.Metabolic syndrome raises the risk of developing Parkinson's disease.Both hypoglycemia and higher levels of HbA1c are associated with the development of dementia.
Source: Journal of Diabetes
Author: Zachary Bloomgarden
Institution: Icahn School of Medicine at Mount Sinai
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,000
OpenAlex ID: W4416335692