Work

Molecular detection of Coxiella burnetii in the blood of febrile patients referred to laboratories and hospitals in Khorramabad, Iran from 2015 to 2016

Year: 2025

Type: article

Abstract: Q fever is a zoonotic infectious disease. Objectives: The objective of this study was to detect the presence of C. burnetii in blood samples of feverish individuals (Contact with livestock; sheep, goats, and cattle, Consumption of unpasteurized dairy products) collected from hospitals at Khorramabad, Iran. A total number of 199 blood samples were collected from patients with fever from August 2015 to November 2016. Nested-PCR, using specific primers targeting the Com1 and icd genes, was employed to diagnose C. burnetii . Out of 199 blood samples, 16 samples were positive with Com1 gene (8%; 95% CI: 5.5-17.4) primers and 13 samples were positive with icd gene (6.5% 95% CI: 3.9%-10.9%) primers (the table 2 is necessary). No significant correlation was observed between the variables and the positive result of PCR (p<0.05) according to the study conducted using SPSS software. Q fever is present in patients from Khorramabad according to this study. Therefore, it should be considered as one of the possible causes of fever and non-specific symptoms in patients. It should be taken into consideration by health policy makers.

Source: New Microbes and New Infections

DOI: 10.1016/j.nmni.2025.101666

Authors: Farnaz Ferdosi, Amin Jaydari, Nemat Shams, Peyman Khademi

Institution: Lorestan University

Language: English

Topic: Vector-borne infectious diseases

Subfield: Parasitology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,770