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PTPRJ-Targeting Peptide Agonist Induces Broad Cellular Signaling Perturbations and DNA Damage in Lung Cancer Cells

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Year: 2025
Type: preprint
Source: bioRxiv (Cold Spring Harbor Laboratory)
DOI: 10.1101/2025.11.17.688709
Authors: Sophie Rizzo, William S. Hart, Rachel L. Fetter, Bokai Song, Forest M. White, Matthew J. Lazzara, Damien Thévenin
Institutions: Lehigh University, University of Virginia, Massachusetts Institute of Technology
Language: English

Topic: Protein Tyrosine Phosphatases
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: National Institutes of Health, National Cancer Institute, National Institute of General Medical Sciences
Awards: Promoting Receptor Protein Tyrosine Phosphatase Activity by Targeting Transmembrane Domain Interactions, University of Virginia Cancer Center Support Grant, Quantitative systems biology of glioblastoma cells and their interactions with the neuronal and immunological milieu
OpenAlex ID: W4416345509
Cites: 105
Cited by:
Related to: 10
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