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Epigenetic Engineering of K562 Cells: Dual-Vector Episomal Strategy for Stable Targeted DNA Methylation using dCas9-DNMT3A and -HDAC1 Fusion Proteins

Year: 2025

Type: article

Source: Journal of Visualized Experiments

DOI: 10.3791/69328

Authors: Irene Dereki, Vasiliki Chondrou, George Lagoumintzis, Argyro Sgourou

Institutions: Hellenic Open University, University of Patras

Language: English

Topic: CRISPR and Genetic Engineering

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W4416355965

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