Work

[Risk factors for white matter damage in preterm infants with necrotizing enterocolitis].

Year: 2025

Type: article

Abstract: OBJECTIVES: To investigate the risk factors for white matter damage (WMD) in preterm infants with necrotizing enterocolitis (NEC). METHODS: A retrospective analysis was conducted on the clinical data of 249 preterm infants with NEC admitted to Children's Hospital of Fudan University between January 2021 and December 2023. Based on brain magnetic resonance imaging (MRI) white matter scores, the infants were categorized into a WMD group (≥7 points) and a non-injury group (<7 points). A multivariable logistic regression analysis was performed to identify risk factors for WMD. RESULTS: <0.05). CONCLUSIONS: Surgical treatment, prolonged hospitalization, and moderate-to-severe VEEG abnormalities are independent risk factors for WMD in preterm infants with NEC, providing a basis for early clinical identification and intervention to improve neurological outcomes.

Source: PubMed

DOI: 10.7499/j.issn.1008-8830.2507132

Authors: Xin Xu, Si-Rui Wang, Peng Zhang, Guo-Qiang Cheng

Institution: Children's Hospital of Fudan University

Language: Chinese

Topic: Neonatal and fetal brain pathology

Subfield: Pediatrics, Perinatology and Child Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4416356151

FWCI:

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