Multidisciplinary treatment vs. non-invasive ventilation for the prognosis of elderly patients with acute exacerbations of chronic obstructive pulmonary disease: A retrospective study
Year: 2025
Type: article
Study design: Observational Study
Abstract: Noninvasive ventilation (NIV) is a pivotal therapeutic modality for acute exacerbations of chronic obstructive pulmonary disease (AECOPD). This study aimed to investigate the efficacy differences between a Multidisciplinary Team (MDT) approach and NIV in elderly AECOPD patients. A single-center retrospective analysis was conducted, encompassing 138 AECOPD patients aged ≥60 years, admitted between 2022 and 2024, with 131 completing the study. Both MDT and NIV achieved efficacy rates exceeding 90%, with no statistically significant differences between the 2 groups in total hospital stay, activities of daily living, Modified Medical Research Council Scale score, oxygenation index, and 1-month readmission rate. Nevertheless, NIV demonstrated superiority in improving dyspnea symptoms compared with MDT (P < .001), while MDT exhibited a greater advantage in reducing partial pressure of carbon dioxide (P = .010). Subgroup analyses revealed that in patients aged ≥75 years and those with an Modified Medical Research Council score of 4, MDT was superior to NIV in partial pressure of carbon dioxide improvement. MDT represents an effective alternative therapeutic option for elderly patients with AECOPD.
Source: Medicine
Authors: Jingyu Kan, Xue Shen, Yanhong Mei, Kui Rui, Jiao Song, Hongchuan Pan
Institutions: Sichuan University, West China Hospital of Sichuan University
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $1,950
OpenAlex ID: W4416364971