Work

Carcinomatous Invasion of Interventricular Septum Mimicking Endocarditis Vegetation

Year: 2025

Type: article

Abstract: BACKGROUND: secondary cardiac tumours are rare and often represent a diagnostic challenge. We report the case of an aortomitral endocarditis associated with a recent history of breast cancer. CASE DESCRIPTION: during the surgery, an unusual "vegetation-like" lesion was identified on the interventricular septum. Despite clinical and pathophysiological characteristics suggesting an infective endocarditis lesion (bacterial grafting onto an irritative lesion of the interventricular septum, secondary to systolic anterior motion of the mitral valve), histopathological examination revealed carcinomatous infiltration of the interventricular septum. CONCLUSION: this case highlights the crucial importance of pursuing anatomopathological analyses in atypical locations of cardiac vegetations, particularly in patients with a history of malignancy, even in remission. Awareness of this diagnostic difficulty can help clinicians to implement rapid and appropriate care.

Source: European Journal of Cardio-Thoracic Surgery

DOI: 10.1093/ejcts/ezaf411

Authors: Calixte de La Bourdonnaye, Sébastien Biedermann, Pierre Allaume, Amedeo Anselmi

Institutions: Inserm, Laboratoire Traitement du Signal et de l'Image, Hôpital Pontchaillou, Centre Hospitalier Universitaire de Rennes, Université de Rennes

Language: English

Topic: Cardiac tumors and thrombi

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4416379101

FWCI:

Cites: 5

Cited by:

Related to: