Year: 2025
Type: article
Abstract: Chi and colleagues revealed that dietary cysteine enhances intestinal stem cell (ISC) regeneration, driving coenzyme A (CoA) synthesis and expansion of intraepithelial (IEL) CD8αβ + T cells that secrete IL-22. This epithelial–immune crosstalk potentiates ISC repair after injury, highlighting a metabolism–immune axis linking cysteine sensing to tissue regeneration.
Source: Trends in Immunology
Authors: Francesco Siracusa, Nicola Gagliani
Institution: University Medical Center Hamburg-Eppendorf
Language: English
Topic: Sulfur Compounds in Biology
Subfield: Biochemistry
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $7,030
Award: G8845622072
OpenAlex ID: W4416386792