Work

Efficacy and Safety of Fluorescent Light Energy (FLE) in the Treatment of Rosacea: A Clinical Study

Year: 2025

Type: article

Abstract: This single-center, randomized, split-face controlled clinical study aims to evaluate the efficacy and safety of Fluorescent Light Energy (FLE) in treating rosacea over a 12-week period with six treatment sessions. Ten subjects are enrolled, with one side of the face receiving a combination of medical skincare hydrogel, Klox® antimicrobial gels, and visible blue light therapy (450±10 nm, 20–50 mW/cm², 10 minutes/session), while the control side receives blue light only. Clinical assessments include CEA scores, lesion counts, FSQ, IGA, and CBS imaging at defined intervals. Blinded evaluators assess outcomes at baseline and follow-up. Preliminary results from five participants suggest favorable safety, tolerability, and potential therapeutic benefit, with one subject opting into extended treatment. Further data are forthcoming.

Source: Photodiagnosis and Photodynamic Therapy

DOI: 10.1016/j.pdpdt.2025.105173

Authors: Ting Liu, Han Ma

Institution: Fifth Affiliated Hospital of Sun Yat-sen University

Language: English

Topic: Acne and Rosacea Treatments and Effects

Subfield: Dermatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,610