Work

Comparison of the efficacy of photodynamic combined laser therapy with cervical circumferential resection for high-grade squamous intraepithelial lesions of the cervix

Year: 2025

Type: article

Abstract: Early treatment of high-grade cervical intraepithelial lesions (HSIL) can effectively reduce the incidence of cervical cancer. At present, HSIL is mainly resected therapy, but surgery often leads to cervical adhesion stenosis and cervical insufficiency, which seriously impact the long-term fertility. To clarify the efficacy of PDT in the treatment of cervical HSIL, and to improve the treatment plan for HSIL. In this essay, a total of 40 women of childbearing age with undifferentiated colposcopy pathology showed HSIL, 20 patients underwent PDT treatment, and 20 patients underwent Loop electro- surgical excision procedure(LEEP), then use spss 27 to analyze the adverse reaction rate, HPV clearance rate, cure rate, improvement rate and progression rate of the two groups after 3 mouths and 9 mouths. In conclusion, the effect of PDT treatment was not weaker than that of the surgical group, and the adverse effects were significantly lower than those of cervical circumferential resection.

Source: Photodiagnosis and Photodynamic Therapy

DOI: 10.1016/j.pdpdt.2025.104920

Author: Mengting Chen

Institution: Minhang District Central Hospital

Language: English

Topic: Cervical Cancer and HPV Research

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,610