Work

Novel Cyanine dye-based photosensitizers for traceable photodynamic therapy

Year: 2025

Type: article

Abstract: Photodynamic therapy (PDT) has gained increasing popularity as a clinical therapeutic method, offering advantages like spatiotemporal controllability, non-invasiveness, and non-drug resistance. Tumor microenvironment (TME)-specific activatable long-wavelength (LW) photosensitizers (PSs) are hopeful to overcome the limitations of traditional PDT, such as systemic phototoxicity and shallow tissue penetration. In recent three years, we have developed a series of TME-activatable PSs based on cyanine dyes for fluorescence and photoacoustic dual-modal imaging guided efficient PDT. The development of novel PSs offers possibilities for clinical alternatives.

Source: Photodiagnosis and Photodynamic Therapy

DOI: 10.1016/j.pdpdt.2025.105196

Author: Jing Lin

Institution: Shenzhen University

Language: English

Topic: Photodynamic Therapy Research Studies

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,610