Work

Observation of the efficacy of photodynamic therapy for recurrent respiratory papillomatosis

Year: 2025

Type: article

Abstract: Significance Photodynamic therapy (PDT) has been proven to be an effective treatment that maximizes the preservation of glottic function. Our objective is to evaluate the effectiveness of PDT in the treatment of recurrent respiratory papillomatosis (RRP). Approach We conducted a retrospective evaluation of patients from January 2020 to October 2024, recording detailed information on their disease, treatment, and follow-up. Results 4 patients underwent PDT with irradiation focused on the glottis, pharynx, and zones I-III of the airway. The average energy used was 3567.6J. 1 month after PDT, the therapeutic effects were evaluated: 1 achieved complete response (CR) and 3 achieved partial response (PR). Progression-free survival (PFS) ranged from 2 to 38 months, and complications were rare. Conclusions PDT may be a safe and effective technique for the treatment of RRP.

Source: Photodiagnosis and Photodynamic Therapy

DOI: 10.1016/j.pdpdt.2025.105072

Authors: Luoqi Yang, Yi Luo, Hang Zou, Hongwu Wang

Institutions: Beijing University of Chinese Medicine, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine

Language: English

Topic: Photodynamic Therapy Research Studies

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,610