Work

Three Decades of Photodynamic Therapy for Glioblastoma: A Comprehensive Scientometric Analysis

Year: 2025

Type: article

Abstract: Significance Photodynamic therapy (PDT) is a promising adjunctive treatment for glioblastoma (GBM), but a comprehensive bibliometric analysis of this field has been lacking. This study provides an in-depth assessment of research trends, key contributors, and hotspots in PDT for GBM. Approach Bibliometric analysis of 799 documents from the Web of Science Core Collection 1993-2024 was conducted using CiteSpace software. Influential contributors and emerging research themes were identified through a 30 year analysis of publication trends, collaborative networks and keyword co-occurrence. Results Publications peaked in 2022, with the United States and China as leading contributors. Notable institutions included the University of California System and Centre National de la Recherche Scientifique. Research has progressed from photodynamic diagnostics to innovative strategies like nanotechnology and combination therapies, addressing tumor heterogeneity and drug resistance. Conclusions This study emphasizes the need for robust interdisciplinary research and clinical translation to enhance its therapeutic potential.

Source: Photodiagnosis and Photodynamic Therapy

DOI: 10.1016/j.pdpdt.2025.104827

Authors: Nan Wang, Jiheng Zhang, Shaoshan Hu

Institution: Zhejiang Provincial People's Hospital

Language: English

Topic: Photodynamic Therapy Research Studies

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,610