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Photodynamic Therapy Effectively Treated Rosacea with Facial Flat Warts Following Unsuccessful Fractional CO2 Laser Treatment: A Case Report

Year: 2025

Type: article

Abstract: Significance Rosacea is a chronic inflammatory skin condition. When combined with facial flat warts, treatment becomes more challenging. Conventional treatments for rosacea may not effectively address the wart lesions, while standard wart treatments can worsen rosacea symptoms. Photodynamic therapy (PDT) has emerged as an effective treatment for rosacea, targeting its inflammatory and microbial factors. This case report explores the effectiveness of PDT in treating rosacea accompanied by facial flat warts. Approach A 31-year-old female with rosacea and flat warts, unresponsive to CO2 fractional laser, received IPL-PDT after standard treatments failed. Clinical evaluation focused on erythema, papules, pustules, and wart resolution. Results After two IPL-PDT sessions, the patient showed significant improvement. The flat warts resolved, and rosacea symptoms, including erythema and papules, were markedly reduced. Conclusions This case demonstrates PDT's effectiveness for rosacea, particularly in patients with coexisting refractory facial flat warts.

Source: Photodiagnosis and Photodynamic Therapy

DOI: 10.1016/j.pdpdt.2025.104809

Authors: Xidie Yin, Yiting Zhao, Liyuan Zhou, Xiuli Wang, Peiru Wang

Institution: Shanghai Skin Disease Hospital

Language: English

Topic: Acne and Rosacea Treatments and Effects

Subfield: Dermatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,610