Work

Analysis of the efficacy of photodynamic therapy for thickened port wine stain

Year: 2025

Type: article

Abstract: Significance Port wine stain is a congenital capillary malformation that is more present on the face and neck. As the patient ages, Port wine stains will gradually darken in color, thicken the skin, and even present nodular hyperplasia. The purpose of this study is to investigate the effect of photodynamic therapy on thickened Port wine stains. Approach A retrospective study was conducted on the records of treatment centers from 2017 to 2024. Analyzed and recorded the types, locations, and treatment effects of skin lesions. Results 205 patients were identified and included, including 69 patients with skin thickening and 136 patients without thickening, aged between 12-58 years old Conclusions The treatment effect of thickened skin lesions is lower than that of non thickened skin lesions. This study suggests that port wine stain lesions should be intervened early, before thickening occurs.

Source: Photodiagnosis and Photodynamic Therapy

DOI: 10.1016/j.pdpdt.2025.104952

Authors: Chenglong Han, Ping Diao

Institution: West China Hospital of Sichuan University

Language: English

Topic: Vascular Malformations and Hemangiomas

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,610