Work

Photodynamic evaluation of curcumin as a larvicide against Aedes aegypti in simulated field conditions

Year: 2025

Type: article

Abstract: Significance This study explore photodynamic inactivation (PDI) as an eco-friendly method for controlling Aedes aegypti larvae using curcumin, a photosensitizer ins a simulated field environment. Approach Photolarvicidal and persistence bioassays were conducted using curcumin formulations at various concentrations in a 100 L fiberglass container filled with dechlorinated water under simulated field conditions. Results The lethal concentrations to eliminate 50% (LC50) and 90% (LC90) of larvae were 2.3 mg/L and 8.7 mg/L, respectively. The residual effect of the curcumin formulation lasted up to 45 days. Conclusions These results indicate that large-scale PDI of Ae. aegypti larvae is a promising method to reduce virus transmission, offering prolonged efficacy in breeding site simulations.

Source: Photodiagnosis and Photodynamic Therapy

DOI: 10.1016/j.pdpdt.2025.104989

Authors: Matheus Garbuio, Alessandra Ramos Lima, Mariana de Souza, Natalia Inada, Vanderlei Salvador Bagnato

Institutions: Universidade Federal de São Carlos, Universidade de São Paulo, Texas A&M University

Language: English

Topic: Photodynamic Therapy Research Studies

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDGs: Good health and well-being, Clean water and sanitation

Open Access status: gold

Estimated APC paid: $2,610