https://www.dirjournal.org/articles/evaluation-of-the-congenital-absence-of-the-vas-deferens-with-magnetic-resonance-imaging-preliminary-findings/doi/dir.2025.253612
Year: 2025
Type: article
Study design: Observational Study
Abstract: To date, no study provides definitive evidence for the pathogenesis of congenital absence of the vas deferens (CAVD).This study aims to evaluate the vas deferens (VD), particularly the intra-abdominal part and accompanying seminal vesicle (SV) pathologies, in search of an explanation for the pathogenesis of the disease using magnetic resonance imaging (MRI) in patients clinically diagnosed with CAVD. METHODSMRI scans of patients admitted to our center with clinically diagnosed unilateral CAVD (CUAVD) or bilateral CAVD (CBAVD) in the infertility clinic were retrospectively evaluated.SV hypoplasia, SV agenesis, the distal part of the VD close to the ampulla, and the intra-abdominal part of the VD were investigated.Additionally, the association of CAVD and SV pathologies was assessed. RESULTSClinically and confirmed with scrotal sonography by evaluating the proximal part of the VD, 32 patients (62.7%) had CBAVD, and 19 patients (37.3) had CUAVD.In MRI, the intra-abdominal part of the VD was visible in 52.9% of all patients.The association between the intra-abdominal part of the VD and CAVD was statistically significant in the CBAVD patient group compared with the CUAVD group (Bonferroni-adjusted P value = 0,006).The intra-abdominal part of the VD dilatation is a new finding in CAVD and was not found in patients with CUAVD.Only 2 out of 51 patients (3.9%) had a standard SV. CONCLUSIONIn the assessment of CAVD and accompanying SV pathologies, detailed findings are obtained by MRI even in the evaluation of the intra-abdominal part of the VD.Preliminary findings in this study are consistent with the theory of acquired vasal agenesis in CBAVD. CLINICAL SIGNIFICANCEThe detailed findings of an MRI may contribute to a better understanding of the disease.
Institution: Erciyes University
Language: English
Subfield: Rheumatology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
Funder: Erciyes Üniversitesi
OpenAlex ID: W4416396044
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