Evaluation of postoperative pain in patients using 8.25 % sodium hypochlorite compared with 5.25 % sodium hypochlorite using sonic and ultrasonic activation methods after single visit root canal treatment: an in-vivo study
Year: 2025
Type: article
Study designs: Randomized Controlled Trial, Clinical Trial
Abstract: Introduction: The aim of this study was to evaluate the postoperative pain in patients using 8.25 % sodium hypochlorite compared to 5.25 % Sodium Hypochlorite concentration without activation and using sonic and ultrasonic activation methods after single visit root canal treatment. Methods: In this double blind randomized trial, a total of 120 participants mandibular premolar with symptomatic irreversible pulpitis were included and randomly divided into 6 groups based on the different concentration of sodium hypochlorite and activation methods (sonic & ultrasonic activation) i.e. Group 1: 5.25 % NaOCl with no activation method, Group 2: 8.25 % NaOCl with no activation method, Group 3: 5.25 % NaOCl with sonic activation, Group 4: 5.25 % NaOCl with Ultrasonic activation, Group 5: 8.25 % NaOCl with sonic activation, Group 6: 8.25 % NaOCl with ultrasonic activation. The presence of postoperative pain was assessed 24, 48, and 72 h after treatment and recorded using the visual analogue scale (VAS). Results: Intragroup postoperative pain in all six groups reduced after 24 h, 48 h and 72 h, showing statistically significant differences. At all-time intervals, postoperative pain was higher in the groups that used ultrasonic stimulation. Conclusion: At all-time intervals, there was no significant difference in the presence of postoperative pain between the 8.25 % NaOCl and 5.25 % NaOCl irrigation solutions with no activation method and sonic activation compared to ultrasonic activation.
Authors: Kabir Bulchandani, Shahina Parvez, Lalit Kumar Likhyani, Manoj Kumar Agarwal, Rohit Kumar Khatri, Deepak Goel
Institution: Rajasthan University of Health Sciences
Language: English
Subfield: Oral Surgery
Field: Dentistry
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $1,800
OpenAlex ID: W4416396375