Three-dimensional visualization of an unusual pulmonary lymphoproliferation after COVID-19
Year: 2025
Type: article
Study design: Case Report
Abstract: The following case report details the case of a 40-year-old Caucasian patient who presented with dyspnea following a serologically confirmed mild-to-severe pulmonary infection with SARS-CoV-2. Chest computer tomography revealed a solitary ground-glass pulmonary nodule in the lower right lobe, measuring 2.1 cm in diameter. Video-assisted thoracoscopic surgery wedge resection revealed well-circumscribed lymphoid aggregates adjacent to the round, smaller airways, bronchioles, and blood vessels. IgKappa B exhibited a monoclonal polyclonal pattern, in contrast to the behavior exhibited by IgKappa A and IgLambda. In the following discussion, the lymphoid lesion was considered in the context of lymphoid hyperplasia, accompanied by an early infiltration of low-grade extranodal B cell lymphoma of the bronchus-associated lymphoid tissue (BALToma).
Source: SAGE Open Medical Case Reports
Institutions: Witten/Herdecke University, Johannes Gutenberg University Mainz, University Medical Center of the Johannes Gutenberg University Mainz, Helios Universitätsklinikum Wuppertal, Universitätsklinikum Aachen, RWTH Aachen University, University of Göttingen, Medizinische Hochschule Hannover, German Center for Lung Research, University of Antwerp
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,000
OpenAlex ID: W4416397332