Work

Transcatheter Aortic Valve Replacement for Severe Native Aortic Valve Regurgitation: A Multicenter and International Registry

Year: 2025

Type: article

Study design: Observational Study

Abstract: Transcatheter aortic valve replacement (TAVR) is the standard of care for severe aortic stenosis but remains off-label for pure native aortic regurgitation (NAVR), where the absence of annular calcification and frequent aortic root dilation hinder anchoring and predispose to valve migration and paravalvular leak.1 Dedicated NAVR systems such as JenaValve and J-Valve have shown promise, yet their availability is limited, and the off-label use of commercial transcatheter heart valves (THVs) remains common.

Source: Structural Heart

DOI: 10.1016/j.shj.2025.100762

Authors: Sant Kumar, Ashish Pershad, David Elison, EiEi Thwe, Jacopo Farina, Ahmad Jabri, Ivan Hanson, Amr Abbas, Pedro A. Villablanca, Nezar Falluji, Simone Biscaglia, Carlo Tumscitz, Timothy Byrne, Francesco Saia, Soundos Moualla, Hursh Naik

Institutions: Creighton University, St. Joseph's Hospital and Medical Center, University of Washington, Arizona Heart Hospital, Arcispedale Sant'Anna, Beaumont Hospital, Royal Oak, Henry Ford Hospital, IRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola, Dignity Health

Language: English

Topic: Cardiac Valve Diseases and Treatments

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,340

OpenAlex ID: W4416399594

FWCI: 0.629

Cites: 3

Cited by: 1

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