Work

Diagnosis of Salmonella enterica-induced septic arthritis in a healthy child using metagenomic next-generation sequencing: a case report

Year: 2025

Type: article

Abstract: Salmonella enterica -induced arthritis frequently manifests in children with malignancies, sickle cell disease, immunodeficiency, or undergoing immunosuppressive therapy; however, its incidence in healthy children is rare. Here, we present a case of septic arthritis resulting from S. enterica infection in a previously healthy child, diagnosed utilizing metagenomic next-generation sequencing (mNGS). This case underscores the utility of mNGS in the clinical identification of S. enterica arthritis. Particularly in scenarios where the causative pathogen remains unidentified, mNGS emerges as a pivotal adjunctive diagnostic modality for uncommon pathogens.

Source: Frontiers in Pediatrics

DOI: 10.3389/fped.2025.1704234

Authors: Min Ren, Qiong Liao

Institutions: Sichuan University, West China Second University Hospital of Sichuan University

Language: English

Topic: Orthopedic Infections and Treatments

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,801