Work

Case Report: The crucial role of contrast-enhanced ultrasound and intraoperative ultrasound in diagnosing pediatric pancreatoblastoma

Year: 2025

Type: article

Abstract: Pancreatoblastoma (PB) is a rare malignant neoplasm of the pancreas, primarily affecting children. While some reports have described the imaging characteristics of PB, detailed descriptions of its ultrasound (US) and contrast-enhanced ultrasound (CEUS) features in children are limited. We reported two cases of PB admitted to our hospital with detailed ultrasonographic features. The first case involved a 14-year-old girl who presented with intermittent, unexplained epigastric pain. CEUS revealed a hypoechoic mass with heterogeneous hyperenhancement in the pancreatic head. She underwent pancreaticoduodenectomy and remains disease-free to date. The second case was a 4-year-old boy with a palpable, unexplained mass in the right upper abdomen. US identified a well-defined, heterogeneous mass in the epigastric region with internal point-like hyperechoic areas. The intraoperative US showed portal vein cancer thrombus. He underwent tumor resection along with reconstruction of the portal and superior mesenteric veins. He subsequently received chemotherapy and remained disease-free to date.

Source: Frontiers in Oncology

DOI: 10.3389/fonc.2025.1610618

Authors: Xiangfeng Zeng, Hualin Yan, Jiali Yang, Bo Xiang, Juxian Liu

Institutions: Sichuan University, West China Hospital of Sichuan University

Language: English

Topic: Pancreatic and Hepatic Oncology Research

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,801