EGR1-mediated repression of HDAC2 regulates BDNF-dependent kindling development in a mouse model of pentylenetetrazol-induced epilepsy
Year: 2025
Type: article
Authors: Daisuke Ibi, Keisuke Ishida, Takaaki Kojima, Shuri Yoshida, Anna Suzuki, Serina Suzuki, Mai Yasui, Kotarou Shibuya, Moe Nakanishi, Tomoe Yamagami, Justin M. Saunders, Mario de la Fuente Revenga, Javier Gonzalez-Maeso, Masayuki Hiramatsu
Institutions: Meijo University, Virginia Commonwealth University
Language: English
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
Open Access status: closed
Funders: YOKOYAMA Foundation for Clinical Pharmacology, Takeda Science Foundation, Novartis Foundation, Uehara Memorial Foundation, Takahashi Industrial and Economic Research Foundation, Brain Science Foundation, Daiko Foundation, Ministry of Education, Culture, Sports, Science and Technology, Ministry of Health, Labour and Welfare, Smoking Research Foundation, Hori Sciences and Arts Foundation, Mochida Memorial Foundation for Medical and Pharmaceutical Research, SENSHIN Medical Research Foundation, Meijo University, NOVARTIS Foundation (Japan) for the Promotion of Science, National Institutes of Health, Japan Society for the Promotion of Science, National Institute of Mental Health
Awards: Involvement of serotonin 5-HT2A receptor in the antidepressant effect of ketamine, Elucidation of molecular mechanisms underlying cognitive impairments following antipsychotic treatment, Gut dysbiosis and 5-HT2A dysregulation in a preclinical schizophrenia model, G5237019297, Elucidation of neural and molecular basis underlying antidepressant effect of serotonergic psychedelics, 抗精神病薬が認知機能に与える影響とHDAC2の役割, Function of GPCR heteromeric complexes in brain, ResearchTraining: Psychiatric and Statistical Genetics
OpenAlex ID: W4416409348