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A case of portal vein thrombosis due to cholecystitis: a 10-year follow-up case report

Year: 2025

Type: article

Abstract: We present a rare case of portal vein thrombosis (PVT) secondary to acute cholecystitis with a 10-year follow-up. A 62-year-old man presented with fever and epigastric pain and was diagnosed with acute cholecystitis. Cholecystitis is a rare local intra-abdominal cause of PVT. After antibiotic treatment, jaundice developed, and imaging revealed left PVT. Anticoagulation was initiated, but thrombosis persisted. Despite the persistent thrombus, long-term follow-up revealed no portal hypertension; however, atrophy of the left lobe of the liver was observed. This case highlights the key aspects of the long-term natural history of cholecystitis-associated PVT and underscores the importance of timely diagnosis and management. LEARNING POINTS: Cholecystitis can be a cause of acute portal vein thrombosis.Early anticoagulation therapy is crucial for thrombus resolution.Portal vein thrombosis may lead to localized hepatic atrophy over the long term.

Source: European Journal of Case Reports in Internal Medicine

DOI: 10.12890/2025_005873