Work

Fibrolamellar carcinoma: The role of imaging in diagnosis and management

Year: 2025

Type: article

Abstract: Liver cancer is one of the most prevalent malignancies worldwide, with hepatocellular carcinoma accounting for approximately 80% of primary liver tumors. Fibrolamellar carcinoma is a rare variant that predominantly affects young individuals without underlying liver disease. Due to its nonspecific clinical presentation and the absence of typical risk factors, diagnosis is often delayed until advanced stages. Correlating imaging findings with clinical and histopathological data is essential for accurate diagnosis and effective treatment, highlighting the need for a multidisciplinary approach to managing these rare neoplasms. We present the case of a 15-year-old patient diagnosed with fibrolamellar carcinoma, emphasizing the critical role of imaging in its identification and the importance of an aggressive surgical approach to optimizing long-term outcomes.

Source: Radiology Case Reports

DOI: 10.1016/j.radcr.2025.10.013

Authors: Diana Melo-Alvear, Ana Clarete, Andrés Hernando Tascón-Barona

Institution: Fundación Valle del Lili

Language: English

Topic: Hepatocellular Carcinoma Treatment and Prognosis

Subfield: Hepatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $600