Work

Effects of repetition duration on skeletal muscle hypertrophy in a rat model of resistance exercise

Year: 2025

Type: article

Abstract: Using a rat model, we investigated the hypertrophic effects of resistance exercise with different repetition durations under conditions where the torque-time integrals were matched. The results suggest that exercise with short but not long repetition duration effectively induces muscle hypertrophy. The lack of hypertrophic response or ribosome biogenesis with long repetition duration may not be predicted by acute molecular responses to exercise but may be explained in part by attenuated torque production during exercise.

Source: Journal of Applied Physiology

DOI: 10.1152/japplphysiol.00956.2024

Authors: Hikaru Kato, Takaya Kotani, Yuki Tamura, Karina Kouzaki, Kazushige Sasaki, Koichi Nakazato

Institutions: The University of Tokyo, Nippon Sport Science University

Language: English

Topic: Muscle Physiology and Disorders

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funder: Japan Society for the Promotion of Science