Differential Expression of Long Non-Coding RNAs MALAT1, ANRIL and MEG3 in Radiation-Exposed Breast Cancer.
Year: 2025
Type: article
Abstract: Objective: -in breast cancer. Materials and Methods: were quantified by real-time polymerase chain reaction (PCR). Cell viability in irradiated MCF-7 and MDA-MB-231 cells was evaluated using the MTT colorimetric assay. Results: expression was significantly increased (P=0.006) only in MDA-MB-231 cells. In addition, cell viability in both MCF-7 and MDA-MB-231 lines declined after irradiation. Conclusion: levels, associated with reduced cell viability .These results suggest a potential role for these lncRNAs in radiation-induced cell death.
Source: PubMed
Authors: Zahra Haghshenas, Hossein Mozdarani
Institution: Tarbiat Modares University
Language: English
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W4416411637
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