Work

Osteochondral knee joint lesion treated with an aragonite-based scaffold. 12-year follow-up of the world's first implantation: Case report

Year: 2025

Type: article

Abstract: Articular surface lesions, which include chondral and osteochondral defects, are debilitating and favor the development of osteoarthritis. The long-term follow-up of the world's first case of implantation of an aragonite-based scaffold (Agili-C TM , from CartiHeal) in a chronic post-traumatic osteochondral knee joint lesion (International Cartilage Repair Society (ICRS) grade IV, size 2 cm2) was presented. Over a decade after implantation, the treatment results remained stable, the patient was fully satisfied and was able to resume his pre-injury activities. Despite the partial meniscectomy of the medial meniscus, the degenerative process was successfully contained, with only subtle osteophytes and mild narrowing of the medial compartment. In addition, radiologic monitoring of the restored bone and cartilage tissue showed successful and durable results. Study Design : Case-report (level of evidence: V)

Source: Journal of ISAKOS Joint Disorders & Orthopaedic Sports Medicine

DOI: 10.1016/j.jisako.2025.101040

Authors: Matej Drobnič, Elizaveta Kon, Dror Robinson, Matic Kolar, Nir Altschuler

Institutions: University of Ljubljana, Ljubljana University Medical Centre, Humanitas University, IRCCS Humanitas Research Hospital, Rabin Medical Center

Language: English

Topic: Osteoarthritis Treatment and Mechanisms

Subfield: Rheumatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,000