Work

Rare germline JAK/STAT variants in a Korean cohort amplify innate immune responses to vaccination

Year: 2025

Type: article

Abstract: method to functionally assess the biological significance of missense mutations in key immune signaling pathways.

Source: iScience

DOI: 10.1016/j.isci.2025.114110

Authors: Hye Kyung Lee, Gyuhyeok Cho, Jin Won Huh, Priscilla A. Furth, Jungwook Kim, Lothar Hennighausen

Institutions: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Gwangju Institute of Science and Technology, Asan Medical Center, University of Ulsan

Language: English

Topic: Immunodeficiency and Autoimmune Disorders

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,240

Funders: Institute for Research on Poverty, U.S. Department of Health and Human Services, Ministry of Health and Welfare, Korea Health Industry Development Institute, National Research Foundation of Korea, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases

Awards: G1247104399, G3421944944, G782557448

OpenAlex ID: W4416420648

FWCI: 0.304

Cites: 58

Cited by: 1

Related to: