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Systemic metabolite kinetics mirror skeletal muscle energy metabolism during acute aerobic exercise

Year: 2025

Type: article

Abstract: In our study, we provide detailed serum kinetics of energy-related metabolites during acute aerobic exercise and after 1 h of recovery. Semantic interpretation of our results against the backdrop of fundamental principles of exercise biochemistry indicate that serum metabolites mirror skeletal muscle energy metabolism, thus providing new insights into systemic energy homeostasis and interorgan crosstalk.

Source: American Journal of Physiology-Cell Physiology

DOI: 10.1152/ajpcell.00715.2025

Authors: David Walzik, Charlotte Wenzel, Jule Elisabeth Strotkötter, Leon Hoenen, Tiffany Y. Wences Chirino, Sina Trebing, Adrian McCann, Per Magne Ueland, Philipp Zimmer, Niklas Joisten

Institutions: TU Dortmund University, Bevital (Norway)

Language: English

Topic: Exercise and Physiological Responses

Subfield: Rehabilitation

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4416422166

FWCI: 0.94

Cites: 26

Cited by: 3

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