Year: 2025
Type: article
Abstract: This report details the development of a conformationally switchable artificial metalloprotein (swArM) that provides differential MRI contrast signal in the presence and absence of the key biomarker glutamine.
Source: Chemical Science
DOI: 10.1039/d5sc05987a
Authors: Charles A. Wilson, Austin T. Bruchs, Saman Fatima, David G. Boggs, Jennifer Bridwell-Rabb, Lisa Olshansky
Language: English
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
Open Access status: diamond
Funders: Department of Economics, College of Literature, Science, and the Arts, U.S. Department of Energy, Searle Scholars Program, National Institutes of Health, Office of Science, National Institute of General Medical Sciences, Basic Energy Sciences, Biological and Environmental Research, SLAC National Accelerator Laboratory
Awards: G1229526393, G1286251239, G2371548206, G262532246, G303061748, G315621713, Paragons of Conformational Control in Metalloenzyme Reactivity, G4235786860, G4399011821, G4581610328, G495301720, G498139845, G5570207115, G6550344761, G7283024673, G7396808078, G7863156295, G8382000481, G8925327636, A Synchrotron Radiation Structural Biology Resource, G911061179, G969889393
OpenAlex ID: W4416422775