Work

Follicular Mucinosis in a Young Male: A Case Report and Literature Review

Year: 2025

Type: article

Abstract: Follicular mucinosis (FM), also known as alopecia mucinosa, is an uncommon cutaneous mucinosis defined by the deposition of glycosaminoglycan-rich mucin within the pilosebaceous unit. This abnormal accumulation primarily affects the outer root sheath of hair follicles and sebaceous glands, resulting in follicular epithelial degeneration, inflammatory infiltration, and disruption of follicular architecture. Clinically, FM manifests as erythematous papules, indurated plaques, and localized areas of alopecia. We present the case of a 21-year-old male with a five-month history of a localized forehead lesion that demonstrated characteristic clinical and histopathologic features of FM, followed by a concise review of relevant literature.

Source: Cureus

DOI: 10.7759/cureus.97338

Authors: Nourah Alazemi, Dana B Sakhi, Fatema Shamsaldeen, Humoud Al-Sabah

Institutions: Kuwait Institute for Medical Specialization, Ministry of Health, Farwaniya Hospital

Language: English

Topic: Skin Diseases and Diabetes

Subfield: Dermatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4416424017