Work

From milk to maturity: The potential for lactocrine programming of heifer reproduction

Year: 2025
Type: article
Abstract: Standard dairy calf management sees that calves are fed a consistent liquid diet until weaning at ∼60 d of age, which is generally provided as whole milk from the bulk tank (a composite of all lactating cows) or a commercial milk replacer product. Although these diets aim to satisfy the nutritional needs of the calf, their composition is not similar to the transient profile of hormones and nonnutritive bioactive factors in the milk the dam produces at this stage. Inclusion or exclusion of hormones in milk during this time may have substantial effects on reproductive programming via lactocrine signaling. This review proposes 4 potential lactocrine factors (IGF-1, insulin, estradiol, and progesterone) relevant to current dairy calf feeding strategies and highlights known interactions within female reproductive development, wide knowledge gaps, and opportunities for further investigation.
Language: English
Open Access status: gold
Estimated APC paid: $1,310
OpenAlex ID: W4416427725
FWCI:
Cites: 50
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