Work

Transcatheter hybrid closure of a large muscular ventricular septal defect with severe pulmonary hypertension using a duct occluder

Year: 2025

Type: article

Abstract: BACKGROUND: Apical muscular ventricular septal defects (mVSDs) are surgically challenging because of their location. Although transcatheter device closure is effective in many patients, large apical defects in infants present specific technical limitations and risks. CASE PRESENTATION: A 6-month-old infant (4.5 kg, 62 cm) with severe pulmonary hypertension and marked feeding and respiratory difficulties was found to have a 10 mm apical mVSD. INTERVENTION: The defect was closed using a 10-12 mm arterial duct occluder (PushMed, China) via a hybrid transcatheter approach. OUTCOME: The procedure achieved complete defect closure without immediate complications. At 3 months' follow-up the infant demonstrated significant weight gain and clinical improvement. CONCLUSIONS: Hybrid transcatheter closure with an arterial duct occluder can be a feasible and effective option for large apical mVSDs in select infants. Careful patient selection and close follow-up remain essential.

Source: Clinical and Experimental Hypertension

DOI: 10.1080/10641963.2025.2586068