Year: 2025
Type: article
Abstract: Description The Multipro® Human Discovery Panel Unlocks Comprehensive Single-Cell Immune Profiling Advancing the understanding of immunology requires tools that capture the complexity and diversity of the human immune system. The Multipro® Human Discovery DNA-barcoded Antibody Panel seamlessly integrates with the 10x Genomics Chromium Single-cell Gene Expression Flex workflow, providing a comprehensive and highly sensitive approach for profiling expression of over 326 validated protein biomarkers at single-cell resolution. With an expansive selection of cell surface, intracellular, signaling and immune pathways, this pre-titrated panel enables researchers to dissect the cellular and molecular mechanisms underlying immune responses, autoimmunity, and immunotherapies. Here we present data to demonstrate the utility of high-plex DNA-barcoded antibody panels in immune discovery work by exploring protein and gene expression networks, including JAK/STAT, NFkB, IFN, and many more signaling pathways. Topic Categories Computational and Systems Immunology (COMP)
Source: The Journal of Immunology
Authors: Austen Michalak, Ivan Godinez
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W4416446340
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