Work

Red Man Syndrome Diagnosed in an Orthopedic Patient

Year: 2025

Type: article

Abstract: Red man syndrome (RMS) is an allergic reaction to vancomycin. Following an intravenous administration of vncomycin, it manifests as a rash on the face, neck, and upper trunk. No such incident has ever been documented in Ghana. Here, we talk about a rare incident of RMS in an orthopedic patient. She received 500 mg of intravenous Vancomycin, which was given over 5 min. She showed signs and symptoms of an allergic reaction 90 s after the administration of the drug and was further resuscitated for about 30 min. She underwent surgery successfully, recovered fully, and was discharged home in a stable condition. Common signs and symptoms of RMS include nausea, malaise, hypotension, and an erythematous rash on the face, arms, and upper trunk. Early resuscitative measures are paramount in preventing severe complications, including cardiac arrest.

Source: Clinical Case Reports

DOI: 10.1002/ccr3.71492

Authors: Kwabena Poku‐Yeboah, Patience Adjepong, Akosua Adoma Antwi‐Kwarteng, Urijah Ntiamoah Osei Mensah

Institutions: Komfo Anokye Teaching Hospital, Kwame Nkrumah University of Science and Technology

Language: English

Topic: Drug-Induced Adverse Reactions

Subfield: Pharmacology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,820