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The feasibility of using coplanar-only VMAT combined with “Treat” function to replace non-coplanar VMAT for SRS of 2 to 6 brain metastases

Year: 2025

Type: article

Abstract: Background: Recent advancements in radiotherapy technology have made it possible to implement single-isocenter noncoplanar volumetric modulated arc therapy (NC-VMAT) for stereotactic radiosurgery (SRS) of multiple brain metastases (BMs). This study aimed to demonstrate the dosimetric feasibility of combining coplanar-only single-isocenter VMAT with the "Treat" function as a potential alternative to conventional single-isocenter NC-VMAT for intracranial multitarget SRS. Methods: ), homogeneity index (HI), beam-on time (BOT), monitoring units (MUs) and delivery accuracy. Results: , along with a higher median gamma passing rate, showing an approximate 2% increase for both the 2%/2 mm and 2%/1 mm criteria. Conclusions: TREAT-CO-VMAT provides high-quality treatment plans and accurate delivery for SRS in patients with 2-6 BMs, making it a promising alternative to conventional NC-VMAT.

Source: Quantitative Imaging in Medicine and Surgery

DOI: 10.21037/qims-2025-570

Authors: Jialu Lai, Shipai Zhu, Jinrong He, Shoupeng Liu, An Li, Jiantao Wang, Renming Zhong

Institutions: Sichuan University, West China Hospital of Sichuan University, State Key Laboratory of Biotherapy, Chengdu Fifth People's Hospital

Language: English

Topic: Advanced Radiotherapy Techniques

Subfield: Radiation

Field: Physics and Astronomy

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4416455086

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