Year: 2025
Type: preprint
Abstract: In this paper, we study an integro-differential equation which describes the evolutionary dynamics of a population structured by a phenotypic trait. This population undergoes asexual reproduction, competition, selection, and mutation. We provide an asymptotic analysis of the model, assuming that the mutations have small effects. A standard approach for the analysis of the qualitative properties of the solutions of such an equation is to apply a logarithmic transformation, which yields a Hamilton-Jacobi equation with constraint. When the reproduction term is a concave function of the trait, it has been established that the solution is classical. We rigorously derive a first-order asymptotic expansion of the solution. This expansion allows us to approximate the moments of the phenotypic density. This result establishes a connection between the approximations of the phenotypic density obtained via the Hamilton-Jacobi approach and relevant biological quantities, which are more suitable from a modeling perspective.
Source: arXiv (Cornell University)
Authors: Guinet, Caroline, Mirrahimi, Sepideh, Roquejoffre, Jean-Michel
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4416456776
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