Year: 2025
Type: article
Abstract: Lumpy Skin Disease (LSD) is a transboundary viral disease of wild and domesticated ruminants, and notifiable to the World Organisation for Animal Health (WOAH). LSD has spread rapidly in the cattle population across the African, European and Asian continents since 1929. Following recent outbreaks in the Southeast Asia region, Singapore observed its first occurrence of LSD in a local dairy cattle farm in March 2022. LSD was confirmed in dairy cattle exhibiting clinical signs with quantitative real-time PCR and sequencing with MinION Nanopore. Analyses of the assembled whole viral genomes also revealed high phylogenetic relatedness to LSD recombinant strains. It remains unclear how the virus was introduced into Singapore, given the absence of known vectors and strict import regulations in place. This highlights the importance of biosurveillance, and laboratory diagnostic readiness to manage outbreaks and prevent the spread of transboundary diseases.
Source: Veterinary Sciences
Authors: Eileen Y. Koh, Adrian K. S. Tan, Yin Cheong Aden Ip, Clara Lau, Jasmine Ong, Oi Wing Ng, Jing Chen, Christine Lee, Suria Fabbri, Juline Chua, Samyuktha Balakumar, Kelvin Ho, Wai Kwan Wong, Brian Z. Y. Tan, Charlene Judith Fernandez, Siow Foong Chang, Him Hoo Yap
Institution: National Parks Board
Language: English
Subfield: Virology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $2,534
Funder: National Parks Board - Singapore
OpenAlex ID: W4416457575