Work

Mepitel Film or StrataXRT for postmastectomy radiation dermatitis: current evidence and implications

Year: 2025

Type: article

Abstract: Acute radiation dermatitis (ARD) is a frequent adverse effect following postmastectomy radiotherapy. Barrier dressings such as Mepitel Film and StrataXRT are increasingly used to prevent or reduce its severity, yet comparative data remain limited. Recent studies, mostly single-center or intra-patient in design with small sample sizes, have demonstrated the effectiveness of both in protection against skin toxicity, although larger multicenter validation is still needed. Within the current evidence base, StrataXRT showed advantages in tolerability, comfort, and application convenience, whereas Mepitel Film use offered slightly greater efficacy against ARD. This letter reviews emerging evidence comparing these two interventions, emphasizing their practical implications for clinical decision-making and future research priorities in ARD prevention.

Source: Annals of Medicine and Surgery

DOI: 10.1097/ms9.0000000000004327

Authors: Saad Arsalan Wasti, Areesha Wasti, Muhammad Usman Iqbal, Naseeb Danaf

Institutions: King Edward Medical University, Lebanese University

Language: English

Topic: Chemotherapy-related skin toxicity

Subfield: Dermatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,850