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Perspective opportunities and challenges in translating dental materials into clinical practice

Year: 2025

Type: article

Abstract: The clinical translation of dental materials presents significant opportunities, driven by increasing market demand, supportive regulatory frameworks, and advancements in digital and additive manufacturing technologies. These factors facilitate enhanced personalization, improved biocompatibility, and superior aesthetic and mechanical properties of dental products. However, the path to successful translation is fraught with challenges, including funding uncertainties, gaps in clinical evaluation frameworks, and limitations in material performance, particularly concerning the long-term stability of resins and zirconia ceramics. Moreover, there is a pressing need for better integration of multidisciplinary data and artificial intelligence technologies. Future advancements in this field will depend on fostering robust collaborations between research and industry, adopting international standards, and leveraging cutting-edge technologies to accelerate innovation.

Source: Translational dental research.

DOI: 10.1016/j.tdr.2025.100061